The MMP3 gene is an important factor in keeping your tendons healthy and influencing their growth and repair. Certain variants of this gene are associated with an increased risk of Achilles ‘tendinopathy’, that is, inflammation, pain, and decreased function. This gene may influence tendon injury through a reduced ability to heal and repair following strenuous exercise or trauma.
COL5A1 is involved in the development of type 5 collagen, a key component in the proper development and function of tendons. Variants of this gene may alter how connective tissue responds to mechanical stress and repetitive use.
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