Insulin and your DNAThe cells in your body use sugar (glucose from carbohydrates) to power many of their functions. Insulin is a key hormone released by your pancreas that processes sugar by allowing your cells to absorb sugar from your blood. If your blood sugar levels are too high, insulin can activate your liver cells to store excess sugar for later use.

Many factors can influence how well your cells respond to insulin, especially your diet. Overeating, high abdominal fat, and a diet high in sugar and fats can change the physiology of your cells, making it more difficult for insulin signals to get where they are needed.

These influences combined with inactivity, can result in tissue inflammation and altered blood chemistry, which can contribute to insulin resistance. Unfortunately, the current prevalence of convenience foods and sedentary lifestyles put most adults at risk of at least some level of insulin resistance later in life.

Your DNA also plays a role in your risk of developing insulin resistance:

  • CEBPA may interact with other genes to influence whether dietary sugars are used for energy or stored in fat cells.
  • The LRP1 gene influences how your body releases insulin and uses glucose by interacting with other genes that send signals to your pancreas.
  • TCF7L2 codes for a signalling chemical that regulates the amount of insulin secretion in the pancreas.

Athletigen can tell you whether your DNA puts you at an increased risk of developing insulin resistance, while also giving expert advice on the steps you can take to lower the risk and stay healthy. Get the Nutrition Report and find out what your nutritional needs are!


Athletigen maintains the highest standards of data privacy and will never sell or share your personal information or data. See our privacy statement and ethics statement for more details. 

Like this article? Spread the word

Share Share Share Share

Purchase DNA insight reports from

Get a DNA consultation